TASIN-1, CAS [[792927-06-1]]

Produktübersicht

• Artikelname: TASIN-1, CAS [[792927-06-1]]
• Artikelnummer: MCE-HY-116572A
• Hersteller Artikelnummer: HY-116572A
• Alternativnummer: MCE-HY-116572A-5MG,MCE-HY-116572A-10MG,MCE-HY-116572A-25MG,MCE-HY-116572A-50MG,MCE-HY-116572A-100MG,MCE-HY-116572A-10MMX1ML
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

TASIN-1 is a selective inhibitor of truncated APCTR (adenomatous polyposis coli gene) that exerts cytotoxic effects by inhibiting cholesterol biosynthesis. TASIN-1 specifically targets colorectal cancer (CRC) cells carrying APC truncated mutations, while having no significant toxicity to wild-type APC cells. TASIN-1 exerts cytotoxic effects by targeting Emopamil binding protein (EBP) to inhibit cholesterol biosynthesis, triggering endoplasmic reticulum (ER) stress, reactive oxygen species (ROS) generation, and JNK-mediated apoptosis, and inhibiting Akt survival signaling. TASIN-1 can be used to prevent and intervene in APC mutant colorectal cancer[1][2][3].

Produkteigenschaften

• Molekulargewicht: 352.49
• Reinheit: 98.09
• CAS Nummer: [792927-06-1]
• Formel: C18H28N2O3S
• Target-Kategorie: Apoptosis,Caspase,JNK,Reactive Oxygen Species (ROS)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound