LY53857 is a potent antagonist of vasoconstriction and serotonin-mediated 5-HT2 receptors. LY53857 did not reduce mean arterial blood pressure in spontaneously hypertensive rats (SHR) at doses that blocked the depressor response to serotonin and blocked central serotonin receptors. In addition, LY53857 was able to enhance neurotransmitter release in rat vas deferens and guinea pig ileal nerves[1].
Molekulargewicht:
500.58
CAS Nummer:
[60634-51-7]
Formel:
C27H36N2O7
Target-Kategorie:
5-HT Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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