E1231, CAS [[1031195-19-3]]

Artikelnummer: MCE-HY-117006
Artikelname: E1231, CAS [[1031195-19-3]]
Artikelnummer: MCE-HY-117006
Hersteller Artikelnummer: HY-117006
Alternativnummer: MCE-HY-117006-10MG,MCE-HY-117006-100MG,MCE-HY-117006-10MMX1ML,MCE-HY-117006-25MG,MCE-HY-117006-5MG,MCE-HY-117006-50MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
Alternative Synonym: 1-{4-[2-(5-Methylfuran-2-yl)quinoline-4-carbonyl]piperazin-1-yl}ethan-1-one
E1231 is an orally active activator of Sirtuin 1 (SIRT1) (EC50=0.83 µM), to modulate cholesterol and lipid metabolism. E1231 interactes with SIRT1 (KD=9.61 µM) and deacetylated liver X receptor-alpha (LXRalpha), and increases ATP-binding cassette transporter A1 (ABCA1) expression. E1231 also reduces atherosclerotic plaque development in ApoE-/- mice model. E1231 can be used for research in cholesterol and lipid disorder-related diseases[1].
Molekulargewicht: 363.41
Reinheit: 98.46
CAS Nummer: [1031195-19-3]
Formel: C21H21N3O3
Target-Kategorie: Sirtuin
Anwendungsbeschreibung: MCE Product type: Reference compound