AMG131 (INT131) is a potent non-thiazolidinedione (TZD) selective peroxisome proliferator-activated receptor gamma modulator (SPPARM). AMG131 binds to PPARgamma within the same binding pocket as the TZDs, but occupies a unique space in the pocket and contacts the receptor at distinct points from the TZDs. AMG131 is promising for research of type-2 diabetes mellitus[1][2][3].
Molekulargewicht:
514.21
Reinheit:
98.99
CAS Nummer:
[315224-26-1]
Formel:
C21H12Cl4N2O3S
Target-Kategorie:
PPAR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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