GSK2945 hydrochloride is a class of tertiary amine, and is a highly specific Rev-erbalpha/REV-ERBalpha (mouse/human reverse erythroblastosis virus alpha) antagonist with EC50s of 21.5 µM and 20.8 µM, respectively. GSK2945 hydrochloride enhances cholesterol 7alpha-hydroxylase (CYP7A1) level and cholesterol metabolism[1].
Molekulargewicht:
457.80
Reinheit:
98.49
Formel:
C20H19Cl3N2O2S
Target-Kategorie:
Cytochrome P450,REV-ERB
Anwendungsbeschreibung:
MCE Product type: Reference compound
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