UKH-1114 is a selective TMEM97 (a sigma-2 receptor) agonist with a Ki values of 1279 and 46 nM for sigma1R and sigma2R/TMEM97, respectively. UKH-1114 exhibits exceptional selectivity with negligible affinity for over 50 other receptors and channels. UKH-1114 effectively relieves spared nerve injury (SNI)-induced mechanical hypersensitivity with a long-lasting duration and without motor impairment. UKH-1114 can be used for neuropathic pain research[1].
Molekulargewicht:
375.43
Reinheit:
99.54
CAS Nummer:
[2113664-14-3]
Formel:
C22H24F3NO
Target-Kategorie:
Sigma Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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