PDK1-IN-2 is a small molecule inhibitor of 3-phosphoinositol-dependent protein kinase-1 (PDK1). PDK1-IN-2 inhibits the binding of PDK1 to its substrate by competitively binding to the PIF pocket of PDK1, thereby inhibiting the kinase activity and downstream signaling of PDK1. PDK1-IN-2 can be used for cell survival and proliferation in cancer[1].
Molekulargewicht:
380.89
Reinheit:
98.90
CAS Nummer:
[1643958-85-3]
Formel:
C15H9ClN2O2S3
Target-Kategorie:
PDK-1
Anwendungsbeschreibung:
MCE Product type: Reference compound
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