Phendioxan is a compound with binding activity at the alpha(1)-adrenaline receptor subtype. The facilitated membrane diffusion of phendioxan is thought to be associated with improved alpha(1d)-AR affinity. Docking simulations of phendioxan at biological targets supported the stoichiometric analysis and revealed the importance of polar, electrostatic, hydrophobic, and shape effects of its phenoxy terminal orthogonal substituents on ligand binding[1].
Molekulargewicht:
421.49
CAS Nummer:
[130905-04-3]
Formel:
C25H27NO5
Target-Kategorie:
Adrenergic Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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