Clitocine, an adenosine nucleoside analog isolated from mushroom, is a potent and efficacious readthrough agent. Clitocine acts as a suppressor of nonsense mutations and can induce the production of p53 protein in cells harboring p53 nonsense-mutated alleles. Clitocine can induce apoptosis in multidrug-resistant human cancer cells by targeting Mcl-1. Anticancer activity[1][2].
Molekulargewicht:
287.23
Reinheit:
95.88
CAS Nummer:
[105798-74-1]
Formel:
C9H13N5O6
Target-Kategorie:
Apoptosis,Bcl-2 Family
Anwendungsbeschreibung:
MCE Product type: Natural Products
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