RB-90740 is a type of biological reducing agent. RB-90740 is activated through metabolic reduction and generates cytotoxic products, thereby selectively killing tumor cells (usually in a hypoxic environment). RB-90740 has selective toxicity towards hypoxic cells, which is mainly achieved by causing DNA strand breaks and activating reducing enzymes (such as Cytochrome P450). RB-90740 does not initially exhibit cytotoxicity similar to its in vitro properties in hypoxic cells in mouse models. RB-90740 can be used to study the tumor physiological environment[1][2]
Molekulargewicht:
362.43
CAS Nummer:
[108307-65-9]
Formel:
C20H22N6O
Target-Kategorie:
Cytochrome P450,DNA/RNA Synthesis
Anwendungsbeschreibung:
MCE Product type: Reference compound
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