all-trans-5,6-epoxy Retinoic acid (5,6-epoxy RA) is an agonist of all isoforms of the retinoic acid receptor (RAR, EC50s=77, 35, and 4 nM for RARalpha, RARbeta, and RARgamma, respectively). 5,6-epoxy RA (1 µM) also induces growth arrest of MCF-7 and NB4 cells in vitro. It is a natural metabolite of all-trans retinoic acid, which is a metabolite of vitamin A.
Molekulargewicht:
316.43
CAS Nummer:
[13100-69-1]
Formel:
C20H28O3
Target-Kategorie:
RAR/RXR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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