EF-1502 is a potent and selective GABA transporter inhibitor with GAT1 and BGT1 inhibitory activity. EF-1502 produces a synergistic anti-epileptic effect when used in combination with Tiagabine (HY-B0696), a compound used to suppress epileptic seizures. The dosing combination of EF-1502 exhibited reduced anti-epileptic efficacy and dyskinesia when used with THIP (HY-10232). The mechanism of EF-1502 differs significantly from Tiagabine, suggesting a unique role in the inhibitory strategy[1].
Molekulargewicht:
414.58
CAS Nummer:
[684645-54-3]
Formel:
C22H26N2O2S2
Target-Kategorie:
GABA Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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