VPC32183 is a competitive antagonist of LPA1 and LPA3 receptors. The activity of VPC32183 can inhibit lipid phosphatase 1 (LPP1), thereby preventing the activation of ERK(1/2) by dioctanoic acid diglyceride (DGPP 8:0). By reducing the expression of LPP1, VPC32183 can further reduce DGPP 8:0-induced ERK(1/2) activation. The effects of VPC32183 suggest that it may have a positive regulatory function in cell signaling processes[1].
Molekulargewicht:
602.74
CAS Nummer:
[717110-61-7]
Formel:
C33H51N2O6P
Target-Kategorie:
Endogenous Metabolite
Anwendungsbeschreibung:
MCE Product type: Reference compound
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