K777 (tosylate), CAS [[502960-91-0]] Preis auf Anfrage
Artikelnummer:
MCE-HY-119293A
Hersteller Artikelnummer:
HY-119293A
Alternativnummer:
MCE-HY-119293A-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
K777 tosylate is a potent, orally active and irreversible cysteine protease inhibitor. K777 tosylate is also a potent CYP3A4 inhibitor with an IC50 of 60 nM and a selective CCR4 antagonist featuring the potent chemotaxis inhibition. K777 tosylate irreversibly inhibits Cruzain, the major cysteine protease of Trypansoma cruzi, and cathepsins B and L. K777 tosylate is a broad-spectrum antiviral by targeting cathepsin-mediated cell entry. K777 tosylate inhibits SARS-CoV and EBOV pseudovirus entry with IC50 values of 0.68 nM and 0.87 nM, respectively[1][2][3].
