Rooperol is a norlignan analog with antitumor, anti-inflammatory, and antioxidant activities. Rooperol induces apoptosis in CSCs through a mitochondrial-induced increase in ROS and a p53-dependent pathway, while also downregulating the expression of key stem cell regulatory factors, such as Oct4, Nanog, and Sox2, ultimately exerting its anticancer effects[1][2][3][4].
Molekulargewicht:
282.29
CAS Nummer:
[83644-00-2]
Formel:
C17H14O4
Target-Kategorie:
Apoptosis,MDM-2/p53,Oct3/4,Reactive Oxygen Species (ROS)
Anwendungsbeschreibung:
MCE Product type: Reference compound
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