ASP9436 is an orally active and blood-brain barrier permeable PDE10A inhibitor with an IC50 of 8 nM against human PDE10A. ASP9436 attenuates locomotor activity in mouse hyperactivity models and ameliorates visual recognition memory impairment in neonatal mice. ASP9436 is applicable to research related to schizophrenia[1].
Molekulargewicht:
498.40
CAS Nummer:
[1401807-89-3]
Formel:
C25H25Cl2N5O2
Target-Kategorie:
Phosphodiesterase (PDE)
Anwendungsbeschreibung:
MCE Product type: Reference compound
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