PBT434 methanesulfonate is a potent, orally active and cross the blood-brain barrier alpha-synuclein aggregation inhibitor. PBT434 methanesulfonate can be used as a iron chelator and modulates transcellular iron trafficking. PBT434 methanesulfonate inhibits iron-mediated redox activity and iron-mediated aggregation of alpha-synuclein. PBT434 methanesulfonate prevents the loss of substantia nigra pars compacta neurons (SNpc). PBT434 methanesulfonate has the potential for the research of Parkinsons disease (PD)[1][2].
Molekulargewicht:
398.26
Reinheit:
99.92
CAS Nummer:
[2387898-69-1]
Formel:
C13H17Cl2N3O5S
Target-Kategorie:
alpha-synuclein
Anwendungsbeschreibung:
MCE Product type: Reference compound
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