BMS-229724 is an orally active and tight-binding cytosolic phospholipase A2 (cPLA2) inhibitor with an IC50 of 2.8 µM. BMS-229724 can inhibit the production of arachidonic acid and eicosanoids in U937 cells, neutrophils, platelets, and other cells. BMS-229724 has anti-inflammatory activity and can be used in the research of diseases such as skin inflammation[1][2].
Molekulargewicht:
589.45
CAS Nummer:
[221914-85-8]
Formel:
C27H25Cl2F3O5S
Target-Kategorie:
Phospholipase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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