Endosidin-2, CAS [[1839524-44-5]]

Artikelnummer: MCE-HY-120821
Artikelname: Endosidin-2, CAS [[1839524-44-5]]
Artikelnummer: MCE-HY-120821
Hersteller Artikelnummer: HY-120821
Alternativnummer: MCE-HY-120821-25MG,MCE-HY-120821-10MG,MCE-HY-120821-5MG,MCE-HY-120821-50MG,MCE-HY-120821-100MG,MCE-HY-120821-10MMX1ML
Hersteller: MedchemExpress
Kategorie: Biochemikalien
Alternative Synonym: ES2
Endosidin-2 (ES2) is a selective inhibitor targeting the conserved exosome subunit EXO70. Endosidin-2 binds to the C-terminal domain of EXO70, inhibiting exocytosis and endosomal recycling, while promoting vacuolar trafficking in plant cells. Endosidin-2 interferes with the EXO70-mediated vesicle-to-plasma membrane anchoring process, leading to abnormal aggregation of auxin transporters (such as PIN2) in the cytoplasm and redirected to vacuolar degradation, while causing abnormal Golgi structure (such as cup-shaped or ring-shaped vesicles cisternae formation). Endosidin-2 can inhibit exocytosis in plant and mammalian cells and is mainly used to study the dynamic regulation of membrane trafficking (such as polar growth, vesicle sorting)[1][2].
Molekulargewicht: 414.17
Reinheit: 99.17
CAS Nummer: [1839524-44-5]
Formel: C15H12FIN2O3
Target-Kategorie: Others
Anwendungsbeschreibung: MCE Product type: Reference compound