(E/Z)-Droloxifene, CAS [[165813-01-4]] Preis auf Anfrage

Produktübersicht

• Artikelname: (E/Z)-Droloxifene, CAS [[165813-01-4]] Preis auf Anfrage
• Artikelnummer: MCE-HY-121149B
• Hersteller Artikelnummer: HY-121149B
• Alternativnummer: MCE-HY-121149B-10MG,MCE-HY-121149B-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: (E/Z)-3-Hydroxytamoxifen

Produktbeschreibung

(E/Z)-Droloxifene is a mixture of (E)-droloxifene (a selective estrogen receptor modulator) and (Z)-droloxifene. (E)-Droloxifene binds to the estrogen receptor (ER) with an IC50 value of 24 nM in rabbit uterine homogenates. (E)-Droloxifene increases uterine weight in immature rats, and reduces estradiol-induced increases in uterine weight in juvenile rats. (E)-Droloxifene also inhibits 17beta-estradiol-stimulated growth of MCF-7, ZR-75-1, and T47D human breast cancer cells. (Z)-Droloxifene binds weakly to ER and has no estrogenic or antiestrogenic activity[1][2][3][4].

Produkteigenschaften

• Molekulargewicht: 387.51
• CAS Nummer: [165813-01-4]
• Formel: C26H29NO2
• Target-Kategorie: Apoptosis,Estrogen Receptor/ERR

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound