Volasertib, CAS [[755038-65-4]]

Produktübersicht

• Artikelname: Volasertib, CAS [[755038-65-4]]
• Artikelnummer: MCE-HY-12137
• Hersteller Artikelnummer: HY-12137
• Alternativnummer: MCE-HY-12137-25MG,MCE-HY-12137-10MMX1ML,MCE-HY-12137-5MG,MCE-HY-12137-10MG,MCE-HY-12137-50MG,MCE-HY-12137-100MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: BI 6727

Produktbeschreibung

Volasertib (BI 6727) is an orally active, highly potent and ATP-competitive Polo-like kinase 1 (PLK1) inhibitor with an IC50 of 0.87 nM. Volasertib inhibits PLK2 and PLK3 with IC50s of 5 and 56 nM, respectively. Volasertib induces mitotic arrest and apoptosis. Volasertib, a dihydropteridinone derivative, shows marked antitumor activity in multiple cancer models[1][2].

Produkteigenschaften

• Molekulargewicht: 618.81
• Reinheit: 99.97
• CAS Nummer: [755038-65-4]
• Formel: C34H50N8O3
• Target-Kategorie: Apoptosis,Polo-like Kinase (PLK)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound