Volasertib (trihydrochloride), CAS [[946161-17-7]] Preis auf Anfrage

Produktübersicht

• Artikelname: Volasertib (trihydrochloride), CAS [[946161-17-7]] Preis auf Anfrage
• Artikelnummer: MCE-HY-12137A
• Hersteller Artikelnummer: HY-12137A
• Alternativnummer: MCE-HY-12137A-10MG,MCE-HY-12137A-50MG,MCE-HY-12137A-100MG,MCE-HY-12137A-25MG,MCE-HY-12137A-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: BI 6727 (trihydrochloride)

Produktbeschreibung

Volasertib (BI 6727) trihydrochloride is an orally active, highly potent and ATP-competitive Polo-like kinase 1 (PLK1) inhibitor with an IC50 of 0.87 nM. Volasertib trihydrochloride inhibits PLK2 and PLK3 with IC50s of 5 and 56 nM, respectively. Volasertib trihydrochloride induces mitotic arrest and apoptosis. Volasertib trihydrochloride, a dihydropteridinone derivative, shows marked antitumor activity in multiple cancer models[1][2].

Produkteigenschaften

• Molekulargewicht: 728.20
• Reinheit: 99.12
• CAS Nummer: [946161-17-7]
• Formel: C34H53Cl3N8O3
• Target-Kategorie: Apoptosis,Polo-like Kinase (PLK)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound