ML367 is a potent inhibitor of ATPase family AAA domain-containing protein 5 (ATAD5) stabilization, acts as a probe molecule that has low micromolar inhibitory activity. ML367 blocks DNA repair pathways, suppresses general DNA damage responses including RPA32-phosphorylation and CHK1-phosphorylation in response to UV irradiation[1].
Molekulargewicht:
334.32
Reinheit:
99.84
CAS Nummer:
[381168-77-0]
Formel:
C19H12F2N4
Target-Kategorie:
Checkpoint Kinase (Chk)
Anwendungsbeschreibung:
MCE Product type: Reference compound
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