Telaglenastat, CAS [[1439399-58-2]]

Produktübersicht

• Artikelname: Telaglenastat, CAS [[1439399-58-2]]
• Artikelnummer: MCE-HY-12248
• Hersteller Artikelnummer: HY-12248
• Alternativnummer: MCE-HY-12248-50MG,MCE-HY-12248-500MG,MCE-HY-12248-10MMX1ML,MCE-HY-12248-25MG,MCE-HY-12248-100MG,MCE-HY-12248-5MG,MCE-HY-12248-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: CB-839

Produktbeschreibung

Telaglenastat (CB-839) is a first-in-class, selective, reversible and orally active glutaminase 1 (GLS1) inhibitor. Telaglenastat selectively inhibits GLS1 splice variants KGA (kidney-type glutaminase) and GAC (glutaminase C) compared to GLS2. The IC50s are 23 nM and 28 nM for endogenous glutaminase in mouse kidney and brain, respectively. Telaglenastat inuduces autophagy and has antitumor activity[1].

Produkteigenschaften

• Molekulargewicht: 571.57
• Reinheit: 99.92
• CAS Nummer: [1439399-58-2]
• Formel: C26H24F3N7O3S
• Target-Kategorie: Autophagy,Glutaminase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound