proMMP-9 inhibitor-3c, CAS [[2138321-18-1]] Preis auf Anfrage
Artikelnummer:
MCE-HY-122585
Hersteller Artikelnummer:
HY-122585
Alternativnummer:
MCE-HY-122585-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
proMMP-9 inhibitor-3c (compound 3c) is a potent proMMP-9 inhibitor. proMMP-9 inhibitor-3c is specific for binding to the proMMP-9 hemopexin-like domain (Kd=320 nM). proMMP-9 inhibitor-3c disruption of MMP-9 homodimerization prevents association of proMMP-9 with both alpha4beta1 integrin and CD44 and results in the dissociation of EGFR. This disruption results in decreased phosphorylation of Src and its downstream target proteins focal adhesion kinase (FAK) and paxillin (PAX)[1].
Molekulargewicht:
361.43
CAS Nummer:
[2138321-18-1]
Formel:
C18H20FN3O2S
Target-Kategorie:
FAK,MMP,Src
Anwendungsbeschreibung:
MCE Product type: Reference compound
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