UC-773587 is a selective SOS1 catalytic activity inhibitor. UC-773587 binds to the catalytic site of Sos1 over HRas and ITSN (a RhoGEF) and inhibits nucleotide exchange with an IC50 value of 4.5 µM. UC-773587 mappes to the Ras switch II interaction region of the Sos1 catalytic site. UC-773587 can be used for the study of prostate cancer[1][2].
Molekulargewicht:
431.42
CAS Nummer:
[116679-70-0]
Formel:
C28H15O5
Target-Kategorie:
SOS1
Anwendungsbeschreibung:
MCE Product type: Reference compound
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