DD-03-171, CAS [[2366132-45-6]]

Produktübersicht

• Artikelname: DD-03-171, CAS [[2366132-45-6]]
• Artikelnummer: MCE-HY-122830
• Hersteller Artikelnummer: HY-122830
• Alternativnummer: MCE-HY-122830-100MG,MCE-HY-122830-5MG,MCE-HY-122830-25MG,MCE-HY-122830-10MMX1ML,MCE-HY-122830-10MG,MCE-HY-122830-50MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

DD-03-171 is a PROTAC BTK degrader. DD-03-171 inhibits mantle cell lymphoma (MCL) cell proliferation (IC50 = 5.1 nM) and prolongs the survival of mice bearing a lymphoma PDX model by degrading BTK, IKFZ1, and IKFZ3. DD-03-171 also inhibits platelet function and thrombosis. (Pink: BTK ligand 9 (HY-168292), Black: linker (HY-28875), Blue: Thalidomide-NH-CH2-COOH (HY-131717))[1][2][3].

Produkteigenschaften

• Molekulargewicht: 991.14
• Reinheit: 98.72
• CAS Nummer: [2366132-45-6]
• Formel: C55H62N10O8
• Target-Kategorie: Btk,NF-kappaB,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound