(3S,5S,6R)-Navtemadlin, CAS [[2459946-14-4]]

Produktübersicht

• Artikelname: (3S,5S,6R)-Navtemadlin, CAS [[2459946-14-4]]
• Artikelnummer: MCE-HY-12296A
• Hersteller Artikelnummer: HY-12296A
• Alternativnummer: MCE-HY-12296A-5MG,MCE-HY-12296A-10MG,MCE-HY-12296A-10MMX1ML,MCE-HY-12296A-50MG,MCE-HY-12296A-25MG,MCE-HY-12296A-100MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: (3S,5S,6R)-AMG 232, (3S,5S,6R)-KRT-232

Produktbeschreibung

(3S,5S,6R)-Navtemadlin is the isomer of Navtemadlin (HY-12296), and can be used as an experimental control. Navtemadlin (AMG 232) is a potent, selective and orally available inhibitor of p53-MDM2 interaction, with an IC50 of 0.6 nM. Navtemadlin binds to MDM2 with a Kd of 0.045 nM[1][2].

Produkteigenschaften

• Molekulargewicht: 568.55
• Reinheit: 99.60
• CAS Nummer: [2459946-14-4]
• Formel: C28H35Cl2NO5S
• Target-Kategorie: MDM-2/p53

Anwendungsbeschreibung

• Anwendungsbeschreibung: Reference compound