Myxochelin A is a microbial metabolite that has been found in A. disciformis and has diverse biological activities. It is active against Gram-positive bacteria, including B. cereus, S. aureus, and M. luteus, but not Gram-negative bacteria or fungi in an agar diffusion assay when used at a concentration of 80 µg/disc. Myxochelin A inhibits 5-lipoxygenase (5-LO) activity with an IC50 value of 1.9 µM for the recombinant human enzyme. It is cytotoxic to 26-L5 colon cancer cells when used at a concentration of 3 µg/mL.
Molekulargewicht:
404.41
CAS Nummer:
[120243-02-9]
Formel:
C20H24N2O7
Target-Kategorie:
Lipoxygenase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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