JNJ-1250132, CAS [[240805-96-3]] Preis auf Anfrage
Artikelnummer:
MCE-HY-123163
Hersteller Artikelnummer:
HY-123163
Alternativnummer:
MCE-HY-123163-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Alternative Synonym:
RWJ-66826, RTI-6617-003
JNJ-1250132 (RWJ-66826) is an orally active and potent steroidal progesterone receptor (PR) antagonist, with an IC50 of 1.3 nM. JNJ-1250132 inhibits binding of the receptor to DNA in vitro. JNJ-1250132 is a potent competitive inhibitor of binding to the human glucocorticoid receptor (GR) (IC50=0.50 nM) and the rat androgen receptor (AR) (IC50=5.6 nM), and was a weak inhibitor of binding to human Estrogen receptor (ER) (IC50 >3000 nM)[1].
