Sul-121 (hydrochloride), CAS [[1541170-25-5]] Preis auf Anfrage
Artikelnummer:
MCE-HY-123461
Hersteller Artikelnummer:
HY-123461
Alternativnummer:
MCE-HY-123461-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Sul-121 hydrochloride is a novel compound with anti-oxidative capacity that effectively inhibits airway inflammation and hyperresponsiveness (AHR) in experimental models of chronic obstructive pulmonary disease (COPD). Sul-121 hydrochloride prevents lipopolysaccharide-induced airway neutrophilia and AHR in a dose-dependent manner. Sul-121 hydrochloride also demonstrates the ability to reduce oxidative stress markers in human airway smooth muscle cells. Sul-121 hydrochloride inhibits nuclear translocation of the NF-kappaB subunit, p65, thereby diminishing pro-inflammatory cytokine release.
Molekulargewicht:
354.87
CAS Nummer:
[1541170-25-5]
Formel:
C18H27ClN2O3
Target-Kategorie:
NF-kappaB
Anwendungsbeschreibung:
MCE Product type: Reference compound
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