RUSKI-201 dihydrochloride is a potent and specific Hedgehog acyltransferase (Hhat) inhibitor with an IC50 of 0.20 µM. RUSKI-201 dihydrochloride is able to block Hh signaling from Shh overexpressing cells and inhibits Hh palmitoylation. RUSKI-201 dihydrochloride is potential Hhat chemical probe in cells and can used in studies of Hhat catalytic function[1].
Molekulargewicht:
430.43
Reinheit:
98.20
CAS Nummer:
[2320262-09-5]
Formel:
C20H29Cl2N3OS
Target-Kategorie:
Hedgehog
Anwendungsbeschreibung:
MCE Product type: Reference compound
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