IRAK4-IN-29, CAS [[1604034-78-7]] Preis auf Anfrage
Artikelnummer:
MCE-HY-123882
Hersteller Artikelnummer:
HY-123882
Alternativnummer:
MCE-HY-123882-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
IRAK4-IN-29 is an IRAK4 inhibitor with good selectivity and low nanomolar activity. IRAK4-IN-29 can effectively block the TLR-mediated signal transduction pathway. IRAK4-IN-29 showed significant inhibitory effects in LPS- and R848-induced cytokine experiments. IRAK4-IN-29 can inhibit LPS-induced TNFalpha in an in vivo model, showing a similar phenotype to IRAK4 gene-deficient mice. IRAK4-IN-29 has good medicinal chemical properties, such as microsomal stability and solubility, showing potential clinical application value[1].
Molekulargewicht:
391.42
CAS Nummer:
[1604034-78-7]
Formel:
C22H21N3O4
Target-Kategorie:
Endogenous Metabolite
Anwendungsbeschreibung:
MCE Product type: Reference compound
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