SR12343, CAS [[2055101-86-3]]

Produktübersicht

• Artikelname: SR12343, CAS [[2055101-86-3]]
• Artikelnummer: MCE-HY-123936
• Hersteller Artikelnummer: HY-123936
• Alternativnummer: MCE-HY-123936-10MG,MCE-HY-123936-1MG,MCE-HY-123936-10MMX1ML,MCE-HY-123936-50MG,MCE-HY-123936-5MG,MCE-HY-123936-25MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

SR12343, an IKK/NF-kappaB inhibitor, is a NF-kappaB essential modulator (NEMO)-binding domain (NBD) mimetic. SR12343 inhibits TNF-alpha- and LPS-induced NF-kappaB activation by blocking the interaction between IKKbeta and NEMO, with an IC50 of 37.02 µM for TNF-alpha-mediated NF-kappaB activation. SR12343 suppresses LPS-induced acute pulmonary inflammation in mice. SR12343 can be used for research of inflammatory and degenerative diseases[1].

Produkteigenschaften

• Molekulargewicht: 368.66
• Reinheit: 99.66
• CAS Nummer: [2055101-86-3]
• Formel: C15H15BrClN3O
• Target-Kategorie: IKK,NF-kappaB

Anwendungsbeschreibung

• Anwendungsbeschreibung: Reference compound