LTbetaR-IN-1 (Compound 919278) is a potent, selective lymphotoxin beta receptor (LTbetaR) inhibitor. LTbetaR-IN-1 also selectively inhibits the nuclear translocation of p52 depended on TNF12A, instead of the nuclear translocation of p65 mediated by TNF-alpha receptor. LTbetaR-IN-1 regulates the NF-kB signaling pathway IN a ligand-independent manner[1].
Molekulargewicht:
320.35
Reinheit:
99.92
CAS Nummer:
[2189366-77-4]
Formel:
C18H16N4O2
Target-Kategorie:
NF-kappaB
Anwendungsbeschreibung:
MCE Product type: Reference compound
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