TC299423 is an orally active, brain-penetrant, selective and potent agonist for alpha6beta2 and alpha4beta2 nicotinic acetylcholine receptors (nAChRs) with anxiolytic and antinociceptive properties. TC299423 acts primarily through alpha6beta2 nAChRs that are implicated in the anxiolytic effects of nicotine. TC299423 elicits reward-related behavior mediated through alpha6beta2 nAChRs in hypersensitive alpha6L90S mice. TC299423 elicits dopamine release and dose not suppress nicotine self-administration in rats. TC299423 is proming for rasearch of addiction and Parkinsons disease[1][2].
Molekulargewicht:
189.26
CAS Nummer:
[1975146-56-5]
Formel:
C11H15N3
Target-Kategorie:
nAChR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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