(R)-Levrazoxane ((R)-ICRF 186) is enzymatically hydrolysed to one-ring open intermediates by dihydropyrimidine amidohydrolase (DPHase), which is present in the liver and kidney. The radiosensitizing efficiency of (R)-Levrazoxane towards EMT6 mouse mammary tumour cells is greater than that of Dexrazoxane (HY-B0581). (R)-Levrazoxane is promising for research of liver and kidney related diseases[1].
Molekulargewicht:
268.27
CAS Nummer:
[24613-06-7]
Formel:
C11H16N4O4
Target-Kategorie:
Drug Intermediate
Anwendungsbeschreibung:
Reference compound
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