DBCO-NHCO-PEG4-amine TFA is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-NHCO-PEG4-amine TFA is a cleavable ADC linker used to conjugate MMAE (HY-15162) and antibody (e.g., DBCO-VCpAB MMAE and DBCO-TRX MMAE with EC50s of 280 nM and 22 nM in SKBR3 cells, respectively)[1].
Molekulargewicht:
637.64
Reinheit:
96.74
Formel:
C31H38F3N3O8
Target-Kategorie:
ADC Linker,PROTAC Linkers
Anwendungsbeschreibung:
MCE Product type: Reference compound
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