GLP-26 is a HBV capsid assembly modulators (CAM), inhibits HBV DNA replication in Hep AD38 system (IC50=3 nM), and reduces cccDNA by >90% at 1 µM. GLP-26 disrupts the encapsidation of pre-genomic RNA, causes nucleocapsid disassembly and reduces cccDNA pools[1]. GLP-26 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Molekulargewicht:
373.35
Reinheit:
98.36
CAS Nummer:
[2133017-36-2]
Formel:
C19H17F2N3O3
Target-Kategorie:
HBV
Anwendungsbeschreibung:
MCE Product type: Reference compound
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