HSP27 inhibitor J2 (J2) is a HSP27 inhibitor, which significantly induces abnormal HSP27 dimer formation and inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of the HSP27 and reducing a cell protection function thereof. HSP27 inhibitor J2 (J2) remarkably enhances the antiproliferative activity of 17-AAG and sensitizes cisplatin-induced lung cancer cell growth inhibition[1][2].
Molekulargewicht:
264.30
Reinheit:
99.70
CAS Nummer:
[2133499-85-9]
Formel:
C13H12O4S
Target-Kategorie:
HSP
Anwendungsbeschreibung:
MCE Product type: Reference compound
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