ENMD-1068 hydrochloride is a selective protease-activated receptor 2 (PAR2) antagonist. ENMD-1068 hydrochloride reduces hepatic stellate cell activation and collagen expression by inhibiting TGF-beta1/Smad signaling. ENMD-1068 hydrochloride also inhibits the proliferation of endometrial cells and induces apoptosis of epithelial cells in the lesion. ENMD-1068 hydrochloride can be used in the study of endometriosis and liver fibrosis[1][2].
Molekulargewicht:
319.87
Reinheit:
98.33
CAS Nummer:
[2703451-51-6]
Formel:
C15H30ClN3O2
Target-Kategorie:
Apoptosis,Protease Activated Receptor (PAR)
Anwendungsbeschreibung:
MCE Product type: Reference compound
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