CMPDA is a positive allosteric modulator of AMPA receptors with EC50s of 45.4 4.2 nM/63.4 5.6 nM for GluA2i/GluA2o receptor. IC50 value: 45.4 4.2 nM/63.4 5.6 nM(GluA2i/GluA2o) [1] Target: AMPAR modulator CMPDA was nearly equipotent at modulating the two isoforms of GluA2 receptors, whereas CMPDB displayed a modest preference for the flip splice variant. Similar to CX614, CMPDA slowed the rate of deactivation of GluA2o receptors approximately 2-fold but had no effect on GluA2i receptor deactivation [1].
Molekulargewicht:
376.53
Reinheit:
99.31
CAS Nummer:
[380607-77-2]
Formel:
C16H28N2O4S2
Target-Kategorie:
iGluR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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