Rivipansel is a small-molecule glycomimetic pan-selectin antagonist with inhibitory activity against E-selectin and P-selectin. Rivipansel binds tightly to the lectin domain of E-selectin, and selectively blocks the recognition of CD62L by E-selectin without affecting the binding of PSGL-1 to E-selectin. Rivipansel functionally inhibits the adhesion of hematopoietic cells to endothelial cells, and is applicable to research related to sickle cell disease[1][2].
Molekulargewicht:
1447.42
CAS Nummer:
[927881-99-0]
Formel:
C58H74N6O31S3
Target-Kategorie:
E-Selectin
Anwendungsbeschreibung:
MCE Product type: Reference compound
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