F81-1144b is a MMP-1 and MMP-3 inhibitor with IC50 values of 5 nM and 29 nM, respectively. F81-1144b reduces serum and hepatic triacylglycerol levels, decreases the secretion of very-low-density lipoprotein-triacylglycerol, inhibits de novo hepatic fatty acid synthesis, and lowers serum insulin and glucose levels. F81-1144b can be used for the research of hypertriglyceridemia[1].
Molekulargewicht:
483.60
CAS Nummer:
[306733-22-2]
Formel:
C27H37N3O5
Target-Kategorie:
MMP
Anwendungsbeschreibung:
MCE Product type: Reference compound
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