(rac)-AR-13503 ((rac)-AR-13324 M1 metabolite) is the isoform of AR-13503 (HY-12798C). AR-13503 a ROCK/PKC inhibitor, inhibiting angiogenesis and enhancing retinal pigment epithelium (RPE) permeability. AR-13503 also inhibits the formation of aberrant neovascularization (NV) in oxygen-induced retinopathy (OIR) model in mice[1][2].
Molekulargewicht:
321.37
Reinheit:
99.08
CAS Nummer:
[1254032-16-0]
Formel:
C19H19N3O2
Target-Kategorie:
PKC,ROCK
Anwendungsbeschreibung:
MCE Product type: Reference compound
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