CP-10 is a PROTAC connected by ligands for Cereblon and CDK, with highly selective, specific, and remarkable CDK6 degradation (DC50=2.1 nM). It inhibits proliferation of several haematopoietic cancer cells with impressive potency including multiple myeloma, and can still degrades mutated and overexpressed CDK6[1].
Molekulargewicht:
871.94
Reinheit:
98.41
CAS Nummer:
[2366268-80-4]
Formel:
C44H49N13O7
Target-Kategorie:
CDK,PROTACs
Anwendungsbeschreibung:
MCE Product type: Reference compound
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