Fluoflavine (ML-090) is a selective NOX1 inhibitor and reactive oxygen species inhibitor. Fluoflavine reduces reactive oxygen species production, NOX1-mediated downstream signaling events, and oxygen-glucose deprivation-induced retinal ganglion cell death. Fluoflavine inhibits NADPH oxidase activity and pathological retinal neovascularization induced by oxygen-induced retinopathy in the retinas of ischemic mice. Fluoflavine can be used in studies related to retinal ischemia-reperfusion injury and proliferative retinopathy[1][2].
Molekulargewicht:
234.26
Reinheit:
99.41
CAS Nummer:
[531-46-4]
Formel:
C14H10N4
Target-Kategorie:
NADPH Oxidase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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