Oxazolone is a haptenizing agent that induces acute or chronic inflammation of the large intestine and is used to construct models of colitis. Oxazolone can cause Th1/Th2-dependent colitis with weight loss and diarrhea. Oxazolone-induced inflammation can be mitigated by neutralizing anti-IL-4 or anti-TNF-alpha antibodies or decoy IL-13R2-alpha-FC proteins[1].
Molekulargewicht:
217.22
Reinheit:
98
CAS Nummer:
[15646-46-5]
Formel:
C12H11NO3
Target-Kategorie:
Interleukin Related,TNF Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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