Entrectinib, CAS [[1108743-60-7]]

Produktübersicht

• Artikelname: Entrectinib, CAS [[1108743-60-7]]
• Artikelnummer: MCE-HY-12678
• Hersteller Artikelnummer: HY-12678
• Alternativnummer: MCE-HY-12678-25MG, MCE-HY-12678-5MG, MCE-HY-12678-10MMX1ML, MCE-HY-12678-100MG, MCE-HY-12678-50MG, MCE-HY-12678-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: NMS-E628, RXDX-101

Produktbeschreibung

Entrectinib (NMS-E628) is an orally active, BBB-penetrated and centrally active inhibitor of TrkA/B/C, ROS1 and ALK, with IC50 values of 1, 3, 5, 12 and 7 nM, respectively. Entrectinib induces apoptosis and cycle arrest in cancer cells, has antitumor activity, and attenuates bleomycin-induced lung fibrosis in mice[1][2][3].

Produkteigenschaften

• Molekulargewicht: 560.64
• Reinheit: 99.87
• CAS Nummer: [1108743-60-7]
• Formel: C31H34F2N6O2
• Target-Kategorie: Anaplastic lymphoma kinase (ALK),Autophagy,ROS Kinase,Trk Receptor

Anwendungsbeschreibung

• Anwendungsbeschreibung: Reference compound