SCH 50911 (hydrochloride), CAS [[160415-07-6]] Preis auf Anfrage
Artikelnummer:
MCE-HY-12783
Hersteller Artikelnummer:
HY-12783
Alternativnummer:
MCE-HY-12783-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
SCH 50911 dihydrochloride is a selective, orally active, blood-brain barrier permeable GABA-B receptor (GABA-B Receptor) antagonist with an IC50 of 1.1 µM in rats. SCH 50911 dihydrochloride blocks baclofen-induced antitussive effects, regulates neuronal firing and GABA release. SCH 50911 dihydrochloride promotes spontaneous seizures during withdrawal in ethanol-dependent rats, alters reward-related neurotransmission, and reduces or suppresses lever responding and self-administration behaviors of alcohol and sucrose in rats. SCH 50911 dihydrochloride is applicable to research related to ethanol withdrawal syndrome, absence epilepsy and alcohol use disorder[1][2][3][4].
Molekulargewicht:
209.67
CAS Nummer:
[160415-07-6]
Formel:
C8H16ClNO3
Target-Kategorie:
GABA Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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